Molecules Against Microbes

Macrocyclic Complexes: Potent Molecules against Drug Resistant Microbes

The metal ion chemistry of macrocyclic ligands has now become a major subdivision of inorganic chemistry and is a growing area of research in inorganic and bioinorganic chemistry. The field of macrocylic chemistry of metals is developing very fast because of its applications and importance in the area of coordination chemistry. Macrocyclic ligands and their transition metal complexes have recei...

Microbes, molecules, maladies and man.

Organohalide respiration: microbes breathing chlorinated molecules.

Bacterial respiration has taken advantage of almost every redox couple present in the environment. The reduction of organohalide compounds to release the reduced halide ion drives energy production in organohalide respiring bacteria. This process is centred around the reductive dehalogenases, an iron-sulfur and corrinoid containing family of enzymes. These enzymes, transcriptional regulators an...

Biofuels: From Microbes to Molecules (Book Review)

A steady and continuous supply of energy will be pivotal if we are to sustain the infrastructure necessary for the current and future development of modern societies. Almost 80% of our current energy supply is derived from the combustion of fossil fuels and, even taking into account the discovery of new reserves, it is predicted that fossil fuel supplies will be severely depleted over the next ...

Algal bioactive diversities against pathogenic microbes

Algae are described as heterogeneous group of organisms with considerable metabolic diversities. Currently, various bioactive compounds are discovered, isolated and used from different classes of algae to develop novel pharmaceuticals. Detectable substances such as, sterols and stanols, isoprenoide, terpenoids, steroid, phenolic compounds, fatty acids, acrylic acid and alkaloids in their extrac...